Felipe Massa made a great start to pass Jenson Button for second place. He pulled alongside pole sitter Lewis Hamilton going into the first chicane, but Hamilton had the inside line and was able to stay ahead. Fernando Alonso was able to make his way up from 10th to 7th place by the end of the first lap, and passed Kimi RÀikkönen for 6th going into the first chicane on the second lap.
On lap 4, Sebastian Vettel passed Michael Schumacher under braking into the first chicane for 4th place. One lap later, Bruno Senna attempted to pass Nico Rosberg around the outside into the first chicane. Senna turned into Rosberg, they banged wheels, and Senna went straight through the chicane to take 11th. Fernando Alonso was able to pass Schumacher coming out of the Parabolica on lap 7.
On lap 8, Bruno Senna tried to pass Paul di Resta on the outside going into the second chicane. Di Resta moved over, forcing Senna onto the gravel. Senna went straight through the chicane and back onto the racing line right in front of Mark Webber, who dodged around him as they entered the first Lesmo corner. On the next lap, Jean-Ăric Vergne had a right rear suspension failure under braking into the first chicane. He spun and slid sideways over one of the curbs, launching his car into the air o...
Jenson Button retook 2nd place from Felipe Massa in the 2nd chicane on lap 19, who was suffering from a loss of telemetry and pitted on lap 20. Fernando Alonso and Sebastian Vettel pitted at the same time on lap 21, and came out right behind Massa with only a car's length separating each of the three. Lewis Hamilton pitted on lap 24, allowing Sergio Pérez, who hadn't pitted yet, to take the lead from 2nd.
On lap 26, Fernando Alonso tried to go around the outside of Sebastian Vettel through Curva Grande. Vettel moved to the outside, pushing Alonso off the track and onto the grass. Alonso managed to keep control of his car and was furious at Vettel's antics. The move was similar to a move Vettel pulled on Alonso the year before, but this time Vettel was given a drive-through penalty. Alonso was able to pass Vettel on lap 29, and the drive-through on lap 35 put Vettel in 9th place behind Webber.